You can have 3 sticks of RAM if your motherboard has three slots available, best to pair up with RAM sticks of the same frequency.

Can I Run 3 Sticks of RAM?
Upgrading your RAM configurations is one of the best ways to improve your CPU performance without overclocking the system. Affixing as many sticks as the mainboard specification surely allows RAM to operate faster.
However, it is preferable to attach paired RAM sticks with a total memory equal to that of triple, considering the dual channel memory is faster. Consequently, the third stick is irrelevant to the dual channel. For example,
3 x 4GB RAM (12 total) is undoubtedly way better than 2 x 4GB (8 total). On the contrary, 2x 6GB (12GB total) is better than 3x 4GB (12 total). In addition, high-speed RAM won’t be your solution if you are waiting on a slow hard disk.
Can a PC Work With 3 Sticks of RAM?
It depends on the slot numbers of the motherboard. Configuration and compatibility are the two most important facts, as well. If your motherboard matches every condition then yes, your PC will run as usual. Not in regular dual channel, but in flex mode. In flex mode, data will be read at single channel speeds from the 3rd stick after using the first 16GB (say, from 2×16 sticks) in dual channel.

Normally, maximum motherboards function a tad faster with equal sizes of paired or quad memory sets. It’s rare for motherboards to own 3 same-size RAM sticks. That being said, some motherboards can include an extra 3rd stick of RAM within their standard specifications. So, look into your motherboard’s user manual to check if you can have 3 sticks of RAM on your PC.
Should You Run Dual Channels With 3 Sticks of RAM?
Generally, it is impossible to run dual channels with 3 sticks of RAM since the setup will eventually direct them to a single channel. However, the good news is, if your computer handles heavy gaming or high-resolution graphics or video editing tasks, your computing system can efficiently run three sticks of RAM as a dual channel.
Before doing this, ensure your PC has a triple-channel system, flex mode tech, or nForce 2 chipset. Therefore, do your research on CPU compatibility before making such a decision. In addition, it’s better to run all RAMs on the same frequency. If not, the faster stick will operate at the frequency of the slower stick. However, they must have the same DDR, or else they won’t fit.
Can You Mix a 3,000 Mhz DDR4 Ram Stick With Two 3200MHZ DDR4 Sticks?
Even at DDR4 3200 MHz, you can mix with a high-end motherboard that allows overclocking. It would be wise to use an identical pair of 3002 MHz RAM with the existing pair of 3200 MHz RAM. All 3 RAM will run at 3000 MHz with synchronization if you can manually overclock the rams. Otherwise, the XMP profiles may clash. As a result, the default running speed will shift to 2133 MHz.
To Conclude
The channel system of your PC determines if you can have 3 sticks of RAM. Paired sticks are always a good idea, compared to the same size memory storage of tripods. Regardless, in case of adapting to more speed & more capacity, 3 sticks RAMs are a better option.
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